The Center for Computational Biology develops new and innovative methods of examining data in the biological sciences whose scale and complexity have historically resisted analysis.
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Genome Diversity Project Reveals Faster Accumulation of Mutations in Non-Africans
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This conclusion and others appear in a report analyzing genome sequence data from 300 individuals from diverse populations
CCB’s mission is to develop modeling tools and theory for understanding biological processes and to create computational frameworks that will enable the analysis of the large, complex data sets being generated by new experimental technologies.
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Research Highlights
A scalable computational platform for Stokes suspensions
We describe a computational framework for simulating suspensions of rigid particles in Newtonian Stokes flow. One central building block is…
Journal of Computational PhysicsSwirling Instability of the Microtubule Cytoskeleton
D. Stein, G. De Canio, E. Lauga, M. Shelley, R. E. Goldstein
In the cellular phenomena of cytoplasmic streaming, molecular motors carrying cargo along a network of microtubules entrain the surrounding fluid.…
BioRxiv: 2020.08.27.268318Metallic Microswimmers Driven up the Wall by Gravity
Q. Brosseau, F. Balboa Usabiaga, E. Lushi, Y. Wu, L. Ristroph, M. D. Ward, M. Shelley, J. Zhang
As a natural and functional behavior, various microorganisms exhibit gravitaxis by orienting and swimming upwards against gravity. Swimming autophoretic nanomotors…
arXiv:2008.05273