CCB Colloquium: Stefano Di Talia

Date & Time

Guest Presenter:
Stefano Di Talia, Ph.D.
Associate Professor of Cell Biology
Duke University School of Medicine

Topic: Waves and flows in embryogenesis and regeneration

Abstract: Embryonic development and tissue regeneration both require a high degree of spatiotemporal coordination. I will describe my lab efforts to understand the synchronization of the cell cycle in early Drosophila embryos and the coordination of tissue growth in zebrafish bone regeneration. I will show how synchronization of the cell cycle in Drosophila embryo is linked to precise nuclear positioning, which is in turn driven by cytoplasmic flows generated by actomyosin cortical contractions. I will also show that excitable waves of Erk activity drive cell and tissue growth in the osteoblast population controlling zebrafish scale regeneration.

About the Speaker

Stefano Di Talia received his BS in Physics from Universita degli studi di Napoli and his Ph.D. in Biomedical Sciences from The Rockefeller Univerisity, where he studied mechanisms of cell size control in budding yeast. He was a postdoc at Princeton University where he started his work on the regulation of the cell cycle during Drosophila embryogenesis. He is currently an Associate Professor in the Department of Cell Biology at Duke University. His lab focuses on dissecting the physical mechanisms that control morphogenesis during embryogenesis and regeneration.

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